Opzelura cream is a medication used to treat mild to moderate atopic dermatitis in adults. It contains the active ingredient ruxolitinib, which is a Janus kinase (JAK) inhibitor that works by blocking certain enzymes that cause inflammation. Here are some details about Opzelura cream:
Positive:
- Opzelura cream has been shown to be effective in reducing the symptoms of atopic dermatitis, such as itching, redness, and scaling.
- It is a topical cream, which means it is applied directly to the skin and does not have to be taken orally.
- According to the FDA, ruxolitinib cream would be the first topical product in its class and would add a new treatment option for patients with atopic dermatitis.
Negative:
- Opzelura cream may cause serious side effects, including serious infections.
- The prescribing information for Opzelura cream warns that it should not be used in patients with a known hypersensitivity to ruxolitinib or any of its components.
- The FDA review of Opzelura cream found that it was negative for QT-prolongation, which is a condition that can cause an irregular heartbeat.
Ingredients or materials:
- The active ingredient in Opzelura cream is ruxolitinib.
- Other ingredients in the cream include: butylated hydroxytoluene, ceteareth-20, cetearyl alcohol, citric acid monohydrate, glycerin, glyceryl monostearate, methylparaben, mineral oil, propylparaben, purified water, and white petrolatum.
