The phrase [rende insensibili al dolore](javascript:void(0)) means "makes (someone) insensitive to pain" in English. This phrase is often used in medical or scientific contexts to describe certain conditions or mutations that cause a person to be unable to perceive physical pain. One such condition is congenital insensitivity to pain, a rare genetic disorder that results in the affected individual not feeling pain despite other sensory perceptions remaining intact. This can be caused by mutations in specific genes (such as SCN9A or ZFHX2) affecting nerve function related to pain signal transmission. People with this condition may not react to injuries or harmful stimuli that normally cause pain and can thus be unaware of potentially serious injuries.
So, "rende insensibili al dolore" literally refers to a factor, gene, mutation, or condition that causes insensitivity or inability to feel pain.
