Retatrutide is a weight loss medication currently in clinical trials that has shown dramatic before-and-after effects with significant weight loss. Trial participants have lost up to 24.2% of their body weight over 48 weeks, with examples including one person going from 210 lbs to 155 lbs, losing 55 lbs. The drug works by mimicking three hormones involved in appetite, metabolism, and blood sugar regulation, leading to suppressed appetite, slower digestion, and increased fat burning. Before starting retatrutide, users often struggle with weight, low energy, and metabolic issues. After usage, many report feeling stronger, leaner, with reduced hunger cravings and improved energy levels. In clinical trials, participants also experienced improvements in blood pressure, blood sugar, cholesterol, and liver fat. However, rapid weight loss with retatrutide may come with side effects such as nausea, diarrhea, constipation, potential pancreatitis, gallstones, muscle loss, and bone weakening. Careful medical supervision is advised during treatment. Summary of retatrutide before and after:
- Before: Overweight or obese, struggle with appetite, energy, and metabolic health.
- After: Significant weight loss (up to ~24%), improved metabolic markers, increased energy, reduced appetite.
- Example: One user lost 55 lbs (210 to 155 lbs), reporting feeling stronger and leaner.
This medication is noted for being more potent than similar drugs like Ozempic and Mounjaro but remains in trials to confirm its safety and efficacy over the long term.
