what are chromosomes?

1 day ago 1
Nature

Chromosomes are long, thread-like structures inside the nucleus of almost every cell that contain the organism’s genetic material. They are made of DNA tightly packed around proteins called histones, which helps fit the DNA into the cell and manage its expression during growth, development, and reproduction. Key points:

  • Structure: Each chromosome is a single molecule of DNA wrapped around histone proteins. In humans, there are 23 pairs (46 total) per cell, with autosomes numbered 1–22 and the sex chromosomes making up the 23rd pair.
  • Function: They organize and protect genetic information, ensure DNA is copied accurately during cell division, and regulate which genes are active in different cells and at different times.
  • Transmission: Chromosomes carry genes, the units of heredity. Offspring inherit one chromosome from each parent for each pair, providing a shared yet unique genetic blueprint.
  • Variation and disease: Changes in chromosome number or structure (like duplications, deletions, or translocations) can disrupt gene function and lead to developmental disorders or diseases.

If you’d like, I can tailor this to a specific audience (kids, students, or adults) or add simple diagrams or analogies to illustrate chromosome structure and mitosis/meiosis.