Naloxone can be administered through various routes, including intranasal spray (into the nose), intramuscular (into the muscle), subcutaneous (under the skin), or intravenous injection. The appropriate dose and route of administration depend on the individuals condition and the situation. For example, intranasal administration is the most common and handy way of administering naloxone, and it is available as a spray. Intramuscular and subcutaneous injections are other common administration routes for naloxone. Intravenous administration is typically reserved for emergency medical professionals. It is important to note that naloxone is not a replacement for proper medical care, and emergency medical assistance should be sought immediately after administering naloxone.