The two main federal agencies that issue guidelines and oversee safety in the workplace in the United States are the Occupational Safety and Health Administration (OSHA) and the Mine Safety and Health Administration (MSHA) . OSHA is responsible for ensuring safe and healthful working conditions for most private sector employees, while MSHA is responsible for ensuring safe and healthful working conditions in mines. These agencies issue regulations for safety and health standards, conduct inspections, and enforce compliance with their standards.