The exact cause of bipolar disorder is unknown, but research suggests that a combination of factors may contribute to the illness. These factors include:
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Genetics: Bipolar disorder often runs in families, and research suggests that genetic factors account for approximately 80% of the cause of the condition. Many genes are involved, and no one gene can cause the disorder.
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Brain chemistry: There is some evidence that bipolar disorder may be associated with chemical imbalances in the brain, particularly with neurotransmitters such as noradrenaline, serotonin, and dopamine.
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Environmental factors: Childhood trauma, stressful life events, and significant environmental stressors such as living with a parent who has a tendency toward mood swings, alcohol or substance abuse, financial and sexual indiscretions, and hospitalizations can trigger bipolar episodes in those who are genetically predisposed.
Its important to note that no single factor can cause bipolar disorder, and the exact combination of factors that lead to the illness can vary from person to person.