The exact cause of narcolepsy is not fully understood, but it is believed to be related to a lack of the brain chemical hypocretin, also known as orexin, which regulates wakefulness. People with type 1 narcolepsy have low levels of hypocretin, and it is thought that the loss of hypocretin-producing cells in the brain may be due to an autoimmune reaction, where the bodys immune system destroys its own cells. Genetics may also play a role in narcolepsy, but the risk of a parent passing the disorder to a child is very low. Other factors that have been suggested as possible triggers of narcolepsy include hormonal changes, major psychological stress, and infections such as swine flu or the medicine used to vaccinate against it. Narcolepsy can cause excessive daytime sleepiness, which can affect personal and professional life, and can also lead to other health conditions such as cardiovascular problems and psychiatric issues. If you suspect you may have narcolepsy, it is important to see a healthcare provider for diagnosis and treatment.