Topical steroid withdrawal is a rare rebound reaction that can occur in patients with topical steroid overuse after discontinuation. When topical steroid medication is stopped, the skin experiences redness, burning, a deep and uncontrollable itch, scabs, hot skin, swelling, stinging, hives, and other symptoms. The following are some of the causes and risk factors of topical steroid withdrawal:
-
Prolonged use of moderate to high strength topical corticosteroids: This is the most common cause of topical steroid withdrawal.
-
Topical corticosteroid use on the face: This is a major risk factor for topical steroid withdrawal.
-
History of atopy: People with a history of atopy are more likely to experience topical steroid withdrawal.
-
Oral corticosteroid use: This is another risk factor for topical steroid withdrawal.
-
Female gender: Women are more likely to experience topical steroid withdrawal.
-
Topical corticosteroid of medium or high potency: Using topical corticosteroids of medium or high potency every day can increase the risk of topical steroid withdrawal.
-
Topical corticosteroid treatment duration of 6 months or more: Using topical corticosteroids for a long period can increase the risk of topical steroid withdrawal.
The exact cause of topical steroid withdrawal is not yet fully understood, but one hypothesis is that it is due to a rebound effect caused by the sudden absence of topical corticosteroids leading to increased inflammation. More research is needed to better understand this condition and establish an optimal treatment plan for topical steroid withdrawal.
