Charlie Kirk made several controversial statements about transgender people, often expressing opposition and using inflammatory language. He described transgender identity as a mental disease needing "brain treatment," refused to use people's correct pronouns, and demanded a nationwide ban on gender- affirming care. He called transgender people an "abomination" and made remarks comparing them negatively using religious scripture. Kirk also opposed transgender athletes competing in women's sports and urged reporting educators who supported gender-affirming ideas. His rhetoric was criticized as hateful and dehumanizing toward transgender individuals, and he was seen as a polarizing figure due to these views.
In one notable incident before his death, he responded to a question about transgender people and mass shootings by saying "Too many," despite statistics showing transgender individuals account for a minimal portion of such events.
Overall, Kirk's discourse on transgender issues was marked by opposition, religiously framed critiques, and calls for legal restrictions on transgender rights, contributing to a highly contentious and divisive legacy around these topics.