Selena Gomez has lupus, an autoimmune condition that causes chronic inflammation in many parts of the body, like the skin, joints, heart, kidneys, lungs, and more. Lupus can lead to a spectrum of symptoms and possible complications, like persistent pain, overwhelming fatigue, skin rashes, frequent fevers, kidney damage, heart problems, and mental health disorders like depression, among others. Selena has been open about her diagnosis with the condition and how it affects her physically and emotionally. In 2017, she revealed that she had a kidney transplant linked to her lupus. She has also undergone chemotherapy for the disease.