Ozempic is not indicated for weight loss. However, it may be prescribed off-label for this use. The starting dose of Ozempic for weight loss is 0.25 mg injected weekly for the first four weeks. After that, the healthcare provider may increase the dose to 0.5 mg once weekly as long as the medication is well-tolerated. The maximum dose of Ozempic is 2 mg once a week. It is important to follow the dosing schedule prescribed by your healthcare provider and to take the lowest effective dose.