Proton pump inhibitors (PPIs) are a group of medications that decrease stomach acid production, helping to relieve symptoms of chronic acid reflux (GERD) and stomach ulcers
. They work by reducing the amount of stomach acid made by glands in the lining of your stomach
. PPIs are available both over the counter and by prescription, and some common brands include Nexium, Prevacid, and Prilosec
. PPIs primarily treat conditions that arise when stomach acid irritates or damages the stomach, duodenum, or food tube (esophagus)
. They block an enzyme called the hydrogen-potassium ATPase pump, or the "proton pump," which is responsible for producing stomach acid
. Although PPIs don't stop the production of all stomach acid, they do reduce the amount produced, allowing the stomach to function properly while minimizing the risk of acid-related damage
. Some key points about PPIs include:
- They are used to treat conditions such as GERD, stomach ulcers, and damage to the lower esophagus caused by acid reflux
- PPIs are available over the counter and by prescription, with various brands and strengths
- The most common side effects may vary depending on the specific PPI medication
It is essential to consult your healthcare provider if you experience any concerning side effects or if your symptoms persist despite taking a PPI
