Berberine is a bitter-tasting and yellow-colored chemical compound found in a variety of plant species, including Berberis vulgaris (barberry), Berberis petiolaris, Berberis aristata (tree turmeric), Berberis thunbergii, Mahonia aquifolium (Oregon grape), Hydrastis canadensis (goldenseal), and Coptis chinensis (Chinese goldthread) . Berberine has been used in traditional Chinese medicine (TCM), Ayurveda, and other medicinal traditions to treat infections, digestive conditions, and inflammatory disorders. It is marketed as a supplement to support healthy blood sugar, cholesterol, and triglyceride levels. Berberine has been shown to have potential health benefits, including lowering blood sugar, reducing cholesterol and triglycerides, and improving heart health. It may also help with weight loss and protect against several chronic conditions. Berberine can be found in the roots, rhizomes, stems, and bark of the plants.