The song "Blister in the Sun" by Violent Femmes is about the feelings that come from drug abuse, as explained by the band's frontman Gordon Gano. Although the lyrics have often been misinterpreted as being about masturbation, Gano has clarified that this was never his intent. The song includes references to being strung out and high, with lyrics such as "I'm high as a kite" and "let me go on like I blister in the sun." The imagery of "big hands" in the song relates to Gano's personal experience of having small hands and a crush on a girl who wouldn't date him because of it. The song's vibe is manic and scattered, inducing a heart-racing euphoria reflective of the drug use theme, but it also captures a youthful, fun, and somewhat silly energy rather than deep meaning.
In sum, "Blister in the Sun" is essentially about the strung-out feelings from drug abuse and youthful exuberance, with a commonly misinterpreted contrast involving masturbation or sexual themes that the songwriter denies.
