what is blocking in statistics

1 year ago 58
Nature

In the statistical theory of the design of experiments, blocking is the arranging of experimental units that are similar to one another in groups (blocks). Blocking is used to control for the effects of nuisance variables, which are sources of variability that are not of primary interest to the experimenter. By blocking on these variables, their effects can be controlled for, leading to greater accuracy in the analysis of the variables of interest.

Heres a step-by-step explanation of how blocking works in statistics:

  1. Identify the nuisance variables: These are the variables that may have an effect on the experimental outcome but are not of primary interest to the experimenter. For example, in a study on the effect of a new diet on weight loss, the nuisance variable could be gender, as it may influence the amount of weight a person can lose, regardless of the diet.

  2. Create blocks: Arrange the experimental units (e.g., individuals) into groups (blocks) that are similar to one another with respect to the nuisance variable. For example, in the diet study, you could create two blocks: one for males and one for females.

  3. Assign treatments: Randomly assign the treatments (e.g., the new diet and a control diet) to the units within each block. This ensures that the effects of the nuisance variable are evenly distributed among the treatment groups.

  4. Analyze the results: Compare the outcomes of the treatments within each block to determine the effect of the variable of interest, while controlling for the effects of the nuisance variable.

Blocking can be used in various fields, such as agriculture, medicine, and genetics, to improve the accuracy and reliability of experimental results.