what is buprenorphine and naloxone sublingual film

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Nature

Buprenorphine and naloxone sublingual film is a medication used to treat opioid use disorder). It contains two medicines: buprenorphine and naloxone. Buprenorphine is a partial opioid agonist, which means it partially works like an opioid but with weaker effects than full agonists like heroin and methadone. It also has a "ceiling effect," which means the opioid effects level off even with further dose increases, reducing the risk of misuse, dependency, and side effects). Naloxone is an opioid antagonist or "blocker" that is only activated in the body if the tablet or film is injected instead of being dissolved in the mouth as prescribed. If naloxone is injected into the bloodstream, it will cause someone who is dependent on opioids to have uncomfortable withdrawal symptoms, which helps discourage people who misuse the medication). The medication comes in the form of a paper-thin, orange-colored rectangular strip that is placed under the tongue to dissolve. It is available in different strengths, including 2 mg/0.5 mg, 4 mg/1 mg, 8 mg/2 mg, and 12 mg/3 mg.