what is ccm

9 months ago 35
Nature

Cerebral Cavernous Malformations (CCMs), also known as cavernomas and cavernous angiomas, are abnormal clusters of closely packed, thin-walled blood vessels known as capillaries that can be found in the brain, spinal cord, or other parts of the body. They are typically diagnosed via MRI when an individual becomes symptomatic and can cause symptoms such as bleeding in the brain, seizures, headaches, and paralysis. CCMs can be inherited, caused primarily by a mutation in one of three CCM genes: CCM1, CCM2, and CCM3. Treatment for CCMs mainly involves surgery, and medications are available to treat symptoms