Creatine is a naturally occurring non-protein compound found in vertebrates, primarily in muscle and brain tissue. It is the primary constituent of phosphocreatine, which is used to regenerate ATP within the cell. Creatine helps create a steady supply of energy in your muscles so they can keep working, especially while you’re exercising. About half of your body’s supply of creatine comes from your diet, especially protein-rich foods such as red meat and seafood. Creatine supplements are popular among bodybuilders and competitive athletes, as they may increase lean muscle mass and enhance athletic performance, particularly during high-intensity, short-duration sports such as weightlifting and high jumping. The most common creatine supplement is creatine monohydrate, which is a dietary supplement that increases muscle performance in short-duration, high-intensity resistance exercises. Other forms of creatine do not appear to have these benefits. Studies suggest that creatine supplements may also help brain function in people 60 and older. However, it is important to talk to a healthcare provider to ensure that creatine supplements are right for you.