Creatine is a natural substance found in muscle cells that helps produce energy during heavy lifting or high-intensity exercise
. It is also found in red meat and seafood
. People commonly take creatine supplements to improve exercise performance, increase muscle mass, and enhance strength
. Creatine is involved in making energy for muscles, and about 95% of it is found in skeletal muscle
. It is also used for muscle cramps, fatigue, multiple sclerosis (MS), depression, and many other conditions, but there is no good scientific evidence to support most of these uses
. Creatine supplements are safe for most people to take, but it is recommended to talk to a healthcare provider before taking them
. The most common and well-researched supplement form is called creatine monohydrate