what is cushings in dogs

Cushings disease, also known as hyperadrenocorticism, is a condition in which the adrenal glands overproduce certain hormones, particularly cortisol, in dogs. This can be caused by a tumor on the pituitary gland or the adrenal glands. The disease typically occurs in middle-aged to older dogs and develops slowly, with early signs that are not always noticeable. Symptoms of Cushings disease in dogs include increased thirst, increased urination, increased appetite, reduced activity, excessive panting, thinning of the skin, hair loss, muscle weakness, and an enlarged abdomen. Veterinarians use blood tests to diagnose Cushings and to differentiate between disease caused by the pituitary or the adrenals. They may also use an ultrasound to help detect a tumor on an adrenal gland. Although Cushings is typically a lifelong condition, the disease usually can be managed with medications. The most common medication used to treat Cushings disease in dogs is Lysodren (mitotane), which destroys the layers of the adrenal gland that produce cortisol. Another medication, Anipryl (selegiline), is FDA-approved to treat Cushings disease in dogs, but only to treat certain cases caused by a pituitary tumor. Health issues caused by Cushing’s disease can be minimized with diligent observation and long-term management.