what is dim supplement

11 months ago 25
Nature

DIM (3,3-Diindolylmethane) is a compound derived from the digestion of indole-3-carbinol, found in cruciferous vegetables such as broccoli, Brussels sprouts, cabbage, and kale. It is sold as a dietary supplement and is under laboratory research to determine its possible biological properties, particularly in anti-cancer mechanisms. DIM has action as a histone deacetylase inhibitor, specifically against HDAC1, HDAC2, and HDAC3. It may help adjust the hormone estrogen and support healthy estrogen levels, and may lower the risk of certain cancers and diseases like lupus that are linked to estrogen. DIM supplements are being studied for their protective effects against certain cancers, to help prevent prostate enlargement, treat acne, aid weight loss, and reduce premenstrual syndrome (PMS) and menopause symptoms. DIM has been taken as a dietary supplement for many years without any reports of adverse effects, and its safety has been evaluated. However, before trying any supplement, it is important to talk to a doctor, as DIM may reduce the effectiveness of some medications.