An EpiPen is an auto-injectable device that delivers the drug epinephrine. It is a life-saving medication used when someone is experiencing a severe allergic reaction, known as anaphylaxis. Epinephrine auto-injectors, including EpiPen, act on the whole body to block the progression of the allergic response. They constrict the blood vessels, leading to increased blood pressure, and decreased swelling. This allows the muscles around the airways to relax, causing the lungs to open. Epinephrine also prevents the release of more allergic chemicals, which stops the progression of the allergic reaction. EpiPen is just one of the brand names of devices known generically as Epinephrine Auto-Injectors. It is important to always have two injectors with you, as each injector works differently. If you have been prescribed EpiPen, you should carry it with you at all times and use it immediately at the first signs and symptoms of a severe allergic reaction. It is also important to call 911 after using EpiPen, as the medicine starts to wear off in 20 to 30 minutes, and the reaction may come back.