what is fpies allergy

11 months ago 15
Nature

Food Protein-Induced Enterocolitis Syndrome (FPIES) is a rare type of non-IgE mediated food allergy that affects the gastrointestinal (GI) tract. Unlike most food allergies, FPIES reactions are delayed and typically occur within hours after eating the trigger food. The most common triggers for infants and children are cow milk, soy, and grains such as rice, barley, and oats. Symptoms of FPIES are usually confined to the gastrointestinal system and include severe vomiting, diarrhea (sometimes bloody), weight loss, dehydration, lack of energy, and failure to thrive. FPIES is frequently misdiagnosed early on as a potential severe blood infection or repeated infections of a gastrointestinal virus. Unlike most food allergies, there is no blood or skin testing available for diagnosis. The primary treatment is strict avoidance of the triggering food. Most children outgrow FPIES by age 3 or 4, but some children will outgrow their allergy earlier or later than this[[2]](https://acaa...