Ketorolac is a nonsteroidal anti-inflammatory drug (NSAID) primarily used for the short-term relief of moderately severe acute pain, often pain that occurs after surgery or other painful procedures. It is effective for managing pain that requires strong analgesia similar to opioids but without the risk of dependence or tolerance. The medication works by blocking cyclooxygenase (COX) enzymes, which reduces the production of prostaglandins responsible for pain, inflammation, and fever
. Common uses of ketorolac include:
- Postoperative pain relief
- Musculoskeletal pain
- Dental pain
- Pain during menstruation (dysmenorrhea)
- Headaches and migraines
- Pain associated with rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis
- Pain from corneal abrasions and inflammation after eye surgery (when used as eye drops)
- Adjunct to opioid therapy to reduce opioid requirements and side effects
Ketorolac is generally prescribed for no longer than five days due to risks of kidney damage and gastrointestinal side effects with prolonged use
. It is available in oral tablets, injectable forms, nasal spray, and eye drops
. In summary, ketorolac is used for short-term management of moderate to severe pain, especially post-surgical pain, and has anti-inflammatory and antipyretic properties
