what is ldl

10 months ago 35
Nature

LDL stands for low-density lipoprotein, which is one of the five major groups of lipoprotein that transport all fat molecules around the body in extracellular water. LDL is sometimes called the "bad" cholesterol because a high LDL level leads to a buildup of cholesterol in the arteries, which can cause health problems such as heart disease and stroke. LDL particles contain a large amount of cholesterol and a smaller amount of proteins, and too much LDL can put you at a higher risk of a stroke or heart disease. LDL delivers fat molecules to cells and is involved in atherosclerosis, a process in which it is oxidized within the walls of arteries. A single LDL particle is about 220–275 angstroms in diameter, typically transporting 3,000 to 6,000 fat molecules per particle, and varying in size according to the number and mix of fat molecules contained within. The common clinical interpretation of blood lipid levels is that high LDL is associated with increased risk of cardiovascular diseases.