Lip fillers are injections that add volume to the lips and are a type of dermal filler. They are made of a variety of materials, including hyaluronic acid, collagen, and other substances. Hyaluronic acid is a natural substance found in the body that helps increase volume in the lips and is the most common material used in lip fillers today. Other materials used in lip fillers include collagen, which was once the most common dermal filler but is used less often today, and other substances. Lip filler companies provide some estimates of the longevity of their products based on clinical studies, and the duration of FDA-approved fillers ranges between a minimum of four to six months and a maximum of 12 months, depending on the product and other factors.