Merkel cell carcinoma (MCC) is a rare and aggressive form of skin cancer that develops in Merkel cells, which are found in the top layer of the skin. These cells are close to the nerve endings responsible for the sense of touch and have substances that act like hormones. MCC usually appears as a flesh-colored or bluish-red nodule, often on the face, head, or neck, but it can also develop on the arms, legs, and trunk.
MCC is a fast-growing cancer that tends to spread quickly to other parts of the body, including nearby lymph nodes, distant lymph nodes or skin, lungs, brain, bones, or other organs. It is the second most common cause of skin cancer death after melanoma. Risk factors for MCC include long-term sun exposure, a weak immune system, fair skin, and age over 50.
The early detection of MCC is crucial for successful treatment. Some of the warning signs of MCC include painless shiny or pearly lesions or nodules, and the "AEIOU" characteristics, which stand for Asymptomatic, Expanding rapidly, Immune suppression, Older than 50 years, and UV-exposed fair skin. If you notice any new or changing lesions on your skin, especially on your face, head, or neck, it is important to schedule an appointment with your doctor for a proper diagnosis and treatment.
