An MPV blood test measures the average size of platelets in the blood. Platelets are small blood cells that help with clotting and are made in the bone marrow. The test is often included in a complete blood count (CBC), which measures many different parts of the blood, including platelets. The MPV test can help diagnose bleeding disorders and diseases of the bone marrow. A low MPV indicates that the average platelet size is small, which may mean that a condition is affecting the production of platelets in the bone marrow. A high MPV indicates a high number of younger, larger platelets in the blood, which may be due to the bone marrow producing and releasing platelets rapidly into circulation. An MPV blood test is used to help diagnose or monitor many blood-related conditions, and it may also be used to help diagnose other health conditions or find out how serious they may be.