Osteoarthritis of the knee, also known as degenerative joint disease, is a condition in which the cartilage in the knee joint breaks down, leading to the bones rubbing together and causing pain, stiffness, and swelling. This condition cannot be cured, but there are treatments available to relieve symptoms and slow its progression. Osteoarthritis of the knee is the most common form of arthritis, and it can affect anyone at any age, although it is more common in women over 50. Common symptoms include knee pain, stiffness, and swelling, which can worsen over time and with activity. Treatment options range from conservative methods to surgical interventions, depending on the severity of the condition and the individuals response to initial treatments. Conservative methods may include weight loss, physical therapy, and medications, while surgical options may include knee replacement or osteotomy, which involves realigning bones to shift body weight away from the affected part of the knee. Complementary and alternative medicine treatments such as acupuncture have also shown promise for managing knee osteoarthritis. Overall, the primary goals of treating osteoarthritis of the knee are to relieve pain and improve mobility.