Pantoprazole is a medication classified as a proton pump inhibitor (PPI) that reduces the amount of acid produced in the stomach. It works by blocking the proton pumps in the stomach lining responsible for acid secretion, thereby decreasing both basal and stimulated gastric acid production
. It is primarily used to treat conditions caused by excess stomach acid, including:
- Gastroesophageal reflux disease (GERD), where stomach acid damages the esophagus causing heartburn and erosive esophagitis
- Stomach ulcers and prevention of gastric damage, especially related to chronic use of NSAIDs
- Zollinger-Ellison syndrome, a rare condition characterized by excessive acid production due to tumors in the pancreas or gut
- It may also be used alongside antibiotics to help eradicate Helicobacter pylori infections
Pantoprazole is available in oral forms (delayed-release tablets and liquid suspension) and as an intravenous injection
. It is usually prescribed for short-term use to allow healing of the esophagus or stomach lining but can be used longer-term for conditions like Zollinger-Ellison syndrome
. Common side effects include headache, diarrhea, abdominal pain, and joint pain. Long-term use can lead to risks such as vitamin B12 deficiency, low magnesium levels, increased risk of bone fractures, and potential kidney problems
. Brand names for pantoprazole include Protonix, Somac, and others, and it is widely prescribed globally
. In summary, pantoprazole is a proton pump inhibitor used to decrease stomach acid production to treat acid-related gastrointestinal conditions, promote healing, and prevent complications from excess acid
