what is pedigree analysis

8 months ago 32
Nature

Pedigree analysis is a method used to study the inheritance of genes in humans and other populations. It involves creating a chart, known as a pedigree chart, to represent a family tree and the inheritance of specific traits or genetic conditions across generations. The analysis helps determine the type of pattern of inheritance, such as whether a trait is dominant, recessive, autosomal, mitochondrial, or sex-linked. It is a valuable tool for understanding the genetic history of families and predicting the probability of an individual or offspring being affected by a particular genetic condition. The chart typically displays family members affected by a specific genetic trait, and by carefully analyzing the chart, one can determine the mode of inheritance and the probability of the trait being passed on to future generations