what is polymyositis

8 months ago 49
Nature

Polymyositis (PM) is one of the inflammatory myopathies, a group of muscle diseases that involve inflammation of the muscles or associated tissues, such as the blood vessels that supply the muscles

. The condition is thought to be an autoimmune disease, where the immune system mistakenly attacks the body's own tissues

. Polymyositis usually affects adults in their 30s, 40s, or 50s, and women are affected more often than men

. The symptoms of polymyositis include:

  • Muscle pain and stiffness
  • Muscle weakness, particularly in the abdomen, shoulders, upper arms, and hips
  • Joint pain and stiffness
  • Trouble catching your breath
  • Problems with swallowing
  • Irregular heart rhythms, if the heart muscle becomes inflamed (myocarditis)

The exact cause of polymyositis is unknown, but it shares many characteristics with autoimmune disorders

. In some cases, the condition may be triggered by a virus or an autoimmune reaction

. Risk factors for polymyositis include having lupus, rheumatoid arthritis, scleroderma, or Sjogren's syndrome

. Polymyositis can lead to great discomfort, but effective treatments are available, and the condition is not generally life-threatening

. Physical therapy is an important component of treatment

. In some cases, the disease may be present in combination with other illnesses, such as cancer