what is reduced glutathione

9 months ago 26
Nature

Reduced glutathione, or GSH, is a crucial antioxidant that supports healthy liver function. It is a tripeptide composed of L-glutamine, L-cysteine, and glycine. In its reduced state, GSH is a major tissue antioxidant that neutralizes reactive oxygen species, preventing damage to important cellular components caused by sources such as free radicals, peroxides, and heavy metals

. GSH also provides reducing equivalents for the reduction of lipid hydroperoxides and hydrogen peroxide. Monitoring reduced GSH and its ratio with oxidized GSSG may be used to evaluate the redox and detoxification status of cells and tissues in relation to the protective role of glutathione against oxidative and free-radical-mediated cell injury