Roaccutane is a brand name for isotretinoin, a medication used to treat severe acne that has not responded to other treatments. It belongs to a group of medications called retinoids and is often prescribed when other acne medications do not work well enough or cannot be tolerated. Roaccutane is taken orally with a glass of water as directed. It helps most people with acne, but it may have unwanted side effects in a few people. Some common side effects of Roaccutane include dry skin, chapped lips, dry eyes, and dry nose. It is important to remember that all medications have potential side effects, and it is essential to talk to a healthcare provider or pharmacist if you have any questions or concerns about taking Roaccutane.