SGOT (serum glutamic oxaloacetic transaminase) and SGPT (serum glutamate pyruvate transaminase) are two common enzymes produced by the liver
. They are generally present within liver cells and, to a lesser extent, in muscle cells
. When the liver is damaged or injured, or if it produces excess enzymes, these enzymes leak out into the blood, causing elevated SGOT and SGPT levels
. The normal range of SGOT and SGPT levels is as follows
:
- SGPT: 7-56 units/liter of serum
- SGOT: 5-40 units/liter of serum
Elevated SGOT and SGPT levels can indicate potential damage or dysfunction of the liver
. Some conditions and diseases that can cause high SGOT and SGPT levels include excessive alcohol consumption, acute viral hepatitis A and B, obesity, heart attack, diabetes, celiac disease, kidney disease, hepatitis C, gallbladder inflammation, muscle injuries, pancreatitis, and more
. An SGOT/SGPT ratio greater than 2 is highly suggestive of alcoholic hepatitis and cirrhosis, occurring in 70% of these patients compared to 26% of patients with postnecrotic cirrhosis, 8% with chronic hepatitis, 4% with viral hepatitis, and none with obstructive jaundice
. To maintain normal SGOT and SGPT levels, it is essential to adopt a healthy lifestyle, including a balanced diet, regular exercise, avoiding excessive alcohol consumption, and getting regular preventive health checkups
. If you suspect liver issues or receive an abnormal test result, it is crucial to consult with a healthcare professional for a comprehensive evaluation and care
