SGPT and SGOT are enzymes produced by the liver and are often measured in a blood test to assess liver function. SGPT, or Serum Glutamic Pyruvic Transaminase, is also known as alanine aminotransferase (ALT). It is an enzyme found in many tissues in the body but is most concentrated in the liver. SGOT, or Serum Glutamic Oxaloacetic Transaminase, also known as aspartate aminotransferase (AST), is an enzyme found in various tissues including the liver, heart, muscle, kidney, and brain, but is most concentrated in the liver.
The normal range of SGPT is between 7-56 units/liter of serum, while the normal range of SGOT is 5-40 units/liter of serum. Elevated levels of SGPT and SGOT can indicate liver damage or injury, as well as other conditions such as heart disease or muscle injury. An SGOT/SGPT ratio greater than 2 is highly suggestive of alcoholic hepatitis and cirrhosis.
High SGPT/SGOT levels can be caused by various conditions and diseases such as excessive alcohol consumption, acute viral hepatitis, obesity, heart attack, diabetes, and others. Maintaining healthy SGPT and SGOT levels can be achieved through dietary interventions and lifestyle modifications.
In summary, SGPT and SGOT are enzymes that play a crucial role in assessing liver function, and their levels can provide valuable information about liver health and potential underlying conditions. Regular health checkups and maintaining a healthy lifestyle are important for monitoring and managing SGPT and SGOT levels.
