Stevens-Johnson Syndrome (SJS) is a rare, serious disorder of the skin and mucous membranes that is usually a reaction to medication
. It is often caused by an adverse drug reaction, particularly to certain types of medications such as epilepsy medicines, antibiotics, and anti- inflammatory painkillers
. In severe cases, it can lead to Toxic Epidermal Necrosis (TEN), which involves more than 30% of the skin surface and extensive damage to the mucous membranes
. Symptoms of SJS include
:
- Fever
- Sore mouth and throat
- Flu-like symptoms (e.g., cough, headache, and muscle aches)
- A painful rash that spreads and blisters
- Blisters and sores on the lips, in the mouth and throat, and in the tube that carries urine out of the body
SJS is more common in children and younger adults but can occur at any age
. People with a weakened immune system, HIV/AIDS, or undergoing chemotherapy are at higher risk of developing SJS
. Infections, such as pneumonia, are the most likely cause of SJS in children, while medications are the most likely cause in adults
. Treatment for SJS requires hospitalization and focuses on removing the cause, caring for wounds, controlling pain, and minimizing complications as the skin regrows
. In severe cases, treatment may include intravenous fluids to prevent dehydration, eye care to prevent eye problems, and wound care to prevent infection and promote healing
. It can take weeks to months to recover from SJS
