Substance abuse, also known as substance use disorder or drug abuse, is a pattern of compulsive use of a substance that leads to significant problems or distress. This can include the misuse of both illegal substances, such as marijuana, heroin, and cocaine, as well as legal substances, such as alcohol, nicotine, and prescription medicines. Substance abuse can result in a range of adverse consequences, including physical, social, and psychological harm, as well as interference with work, school, or home duties. It is a recognized medical brain disorder that can lead to dependence and addiction