A test-tube baby is a term used to refer to a baby conceived through in vitro fertilization (IVF), a process where fertilization is done outside the uterus in a glass vessel by combining a female egg with a male sperm. The term "test- tube baby" was originally used to refer to babies born from the earliest applications of the practice of fertilizing an egg outside of a woman’s body. The first successful IVF was done in 1934, and the world’s first IVF human baby was born in 1978