Testosterone replacement therapy (TRT) is a treatment for men with symptomatic hypogonadism, a condition characterized by low testosterone levels. TRT can be administered through injections, pellets, patches, or gels, and it aims to improve the signs and symptoms of low testosterone, such as low libido, decreased energy levels, and depressive moods
. The benefits of TRT include increased libido and energy levels, improved bone density, muscle mass, and insulin sensitivity, as well as cardioprotective effects
. However, TRT is contraindicated in men with untreated prostate and breast cancer, and it may have side effects such as polycythemia, peripheral edema, and cardiac and hepatic dysfunction
. It's important for men considering TRT to discuss the potential benefits and risks with their doctor, as long-term data on the safety of TRT is still lacking
