The best treatment for diabetic neuropathy in feet involves a combination of medications and lifestyle changes. According to the Mayo Clinic, the American Diabetes Association recommends starting with medications such as pregabalin (Lyrica) or gabapentin (Neurontin) to relieve pain and slow the progression of the disease. Additionally, the use of capsaicin cream applied to the skin can reduce pain sensations in some people. The American Academy of Family Physicians suggests using pregabalin, gabapentin, amitriptyline, or duloxetine as first-line treatments for painful diabetic peripheral neuropathy. Tricyclic antidepressants like amitriptyline are also available for the treatment of chronic pain. Furthermore, WebMD mentions that controlling blood sugar and managing diabetes can help prevent the pain from worsening, and medications such as serotonin and norepinephrine reuptake inhibitors (SNRIs) and antiseizure drugs can help relieve neuropathy. It is important to consult a healthcare provider before using any alternative therapy or dietary supplement to ensure there are no potential interactions. Additionally, lifestyle changes such as wearing hand or foot braces and using orthopedic shoes can also improve the quality of life for individuals with diabetic neuropathy. Therefore, a combination of medication, blood sugar control, and lifestyle adjustments is recommended for the treatment of diabetic neuropathy in feet.