The term "blues" can refer to different drugs depending on the context. One of the drugs referred to as "blues" is oxycodone, a prescription drug used to relieve moderate to severe pain. However, the term "Ts and Blues" refers to a combination of pentazocine and tripelennamine, which is used as a substitute for heroin and is mainly abused intravenously. Pentazocine is a pain medication that is often considered to have low abuse potential in tablet form, but when combined with tripelennamine, it can produce a powerful high. The abuse of Ts and Blues can lead to serious medical complications, including central nervous system complications, seizures, strokes, CNS infections, and hepatic failure. It is important for prescribing physicians to be aware of the abuse potential of these drugs and for individuals to be cautious when using prescription medications obtained from illicit sources, as counterfeit pills are common and can be laced with dangerous substances like fentanyl.