Spice is a nickname for a substance containing one or more synthetic cannabinoids, which are lab-made drugs designed to mimic the effects of tetrahydrocannabinol (THC), the main psychoactive ingredient of marijuana. Synthetic cannabinoids are from the synthetic cannabinoid class of drugs that are often marketed and sold under the guise of “herbal incense” or “potpourri” and are packaged without information as to their health and safety risks. Spice is not a single drug, but a range of laboratory-made chemicals that mimic the effects of THC. Synthetic cannabinoids are sold under names like K2 and Spice, as well as many other names, at small convenience stores, head shops, gas stations, and via the Internet from both domestic and international sources. These products are labeled “not for human consumption” in an attempt to shield the manufacturers, distributors, and retail sellers. Street names for synthetic cannabinoids include Spice, K2, Blaze, RedX Dawn, Paradise, Demon, Black Magic, Spike, Mr. Nice Guy, Ninja, Zohai, Dream, Genie, Sence, Smoke, Skunk, Serenity, Yucatan, Fire, and Crazy Clown. Synthetic cannabis, of which Spice is an example, is linked to serious health issues ranging from difficulties breathing to psychotic episodes.