The lowest oxygen level before death can vary depending on the individual and the circumstances. However, a blood oxygen level below 60 mm Hg can be dangerous, as there may not be enough oxygen reaching the bodys vital organs. A blood oxygen level below 92% and fast, shallow breathing were associated with significantly elevated death rates in a study of hospitalized COVID-19 patients. A blood oxygen level below 95% is not normal, and a level under 90% requires emergency care. Once the level of oxygen goes below 15 percent, serious symptoms of hypoxia begin to show up, which means that someone is risking serious injury or even death. At 10 percent oxygen concentration, somebody has minutes or seconds to survive. It is important to note that these are general guidelines, and the lowest oxygen level before death can vary depending on the individuals health and other factors. If someone is experiencing symptoms of low oxygen levels, they should seek medical attention immediately.