An enlarged heart (cardiomegaly) is not a disease, but rather a sign of another condition that is causing the heart to work harder than normal. The most common cause of an enlarged heart is high blood pressure, which forces the heart to work harder than usual and leads to the wall of the hearts main pumping chamber (the left ventricle) to thicken, a condition known as hypertrophy. Other causes of an enlarged heart include heart valve problems, heart disease, and cardiomyopathy. Cardiomyopathy is a group of diseases that affect the heart muscle and can cause the heart to dilate due to problems with the underlying heart muscle. Other conditions that can lead to an enlarged heart include thyroid disorders, too much iron in the body (hemochromatosis), and congenital heart defects. It's important to follow a healthy lifestyle and have regular health checkups to manage heart disease.