what is tissue perfusion

Tissue perfusion refers to the delivery of blood to a capillary bed in tissue, which is the passage of fluid through the circulatory system or lymphatic system to an organ or a tissue. It is the volume of blood that flows through a unit quantity of the tissue, and is often expressed in unit: ml blood/100 g tissue. Tissue perfusion is crucial to monitor since it indicates the state of the health of a tissue. All animal tissues require an adequate blood supply for health and life. Sufficient tissue perfusion and oxygenation are vital for all metabolic processes in cells and the major influencing factor of tissue repair and resistance to infectious organisms. Oxygen is required for wound healing to occur, therefore, for healing to take place it is essential that there is an adequate tissue perfusion and oxygenation. Tissue perfusion can be measured as the rate at which blood is delivered to tissue, or volume of blood per unit time (blood flow) per unit tissue mass. It can be evaluated on a local tissue level, and many monitoring systems are available for measuring tissue perfusion and oxygenation.