Very-low-density lipoprotein (VLDL) is a type of lipoprotein made by the liver. It is one of the major groups of lipoproteins that transport fats, including triglycerides and cholesterol, through the bloodstream. VLDL mainly carries triglycerides, which are used by body cells for energy or stored as fat. It transports endogenous lipids (produced within the body) from the liver to various tissues. VLDL is considered one of the "bad" forms of cholesterol because high levels of VLDL can lead to plaque buildup in the arteries, increasing the risk of heart disease and stroke. In the bloodstream, VLDL is converted to intermediate-density lipoprotein (IDL) and then to low-density lipoprotein (LDL), which also plays a role in cholesterol transport and cardiovascular risk. Key points about VLDL:
- Made by the liver.
- Transports triglycerides and cholesterol.
- Contains about 70% triglycerides.
- Considered a "bad" cholesterol due to its role in plaque formation in arteries.
- Precursor to LDL in the blood circulation.
- Normal blood levels are typically below 30 mg/dL.
Therefore, VLDL is important for energy transport but high levels are linked to cardiovascular disease risk. It is commonly measured indirectly through blood tests based on triglyceride levels. This summary combines information about physical nature, function, and clinical relevance of VLDL. If you're interested in specific test info or more detailed biochemical composition, I can provide that as well.
