Vancomycin-resistant Enterococci (VRE) are bacteria that have developed resistance to the antibiotic vancomycin. These bacteria are commonly found in the human intestines, female genital tract, and the environment. VRE infections are a concern in healthcare settings, particularly among hospitalized patients and those with a history of prolonged antibiotic use, surgical procedures, or medical device insertions. VRE infections can be serious and difficult to treat, especially when they affect the urinary tract, surgical wounds, or the bloodstream of hospitalized patients. The symptoms of VRE infections are similar to those of other bacterial infections, and they can trigger conditions such as urinary tract infections, bloodstream infections, and wound infections. VRE can be spread through direct contact with infected individuals, contaminated items, or environmental surfaces. Preventive measures include thorough handwashing, cleaning of surfaces, and using appropriate protective equipment when in contact with bodily fluids. Healthcare providers typically use laboratory tests to determine the most effective antibiotics for treating VRE infections. The Centers for Disease Control and Prevention (CDC) tracks VRE infections using data from various sources to address this public health concern.