Brandon Blackstock was battling melanoma, which is a serious and aggressive form of skin cancer. He privately fought this illness for more than three years before passing away peacefully on August 7, 2025, at the age of 48. Melanoma arises from melanocytes, the cells responsible for skin color, and is the most dangerous form of skin cancer because it can rapidly spread to other organs if not detected early. Despite treatment options, advanced melanoma has a high risk due to its aggressive nature. Blackstock's illness was mostly kept private, but his ex-wife, Kelly Clarkson, disclosed that he had been ill in the past year, which led her to postpone several performances of her Las Vegas residency to be fully present for their children during his illness. He died at his home under hospice care, surrounded by family. His family expressed gratitude for the thoughts and prayers they've received and requested privacy during this difficult time. In summary, the main issue with Brandon Blackstock's health was melanoma, which ultimately caused his death after a prolonged and courageous battle. The condition was reported as the cause of death by the Silver Bow County coroner, and the manner of death was natural causes related to this cancer. He experienced seizures as a significant condition contributing to his death but not the direct cause.
